The success of a stem cell transplant depends on how closely the donor and the recipient genetically match. The state of the engraftment will be regularly monitored and is completed between 10 – 28 days after the first session. The first sign is a rise in the white blood cell count which means that the transplant has started making new cells.
Typically a bone marrow transplant recovery time is 3 months but may go up to a year for a full recovery. Recovery depends on many factors including:
Doctors keep a tab on the blood count on a regular basis to check that new blood cells are being produced. They also conduct various blood tests and evaluate the results to confirm that new red and white blood cells and platelets are being produced and also make sure that the patient has been cured completely.Supportive care, antibiotic regimens, and DNA-HLA typing play a significant role in the survival and the quality of life of post-transplant patients.
The post-engraftment phase period may last for months to years. This phase of the patient’s life is marked by the gradual development of tolerance, management of chronic GVHD, weaning off from immunosuppressant and documentation of immune reconstitution. Most of the patients require immunization usually one year after the transplantation. The immunization begins with tetanus (DT) followed by inactivated poliovirus vaccine (IPV), influenza vaccination every year, Haemophilus influenza, pneumococcal and also hepatitis B series.